SCHEMBL7122592

SCHEMBL7122592

O=S(=O)(c1ccccc1)N1CCN(S(=O)(=O)c2ccccc2)CC1

nearest known ligand 0.80

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.80
PKM P14618 2/20 0.77
ALDH1A1 P00352 4/20 0.74
LMNA P02545 2/20 0.74
SMN1; SMN2 Q16637 2/20 0.67
APOBEC3A P31941 1/20 0.67
APOBEC3G Q9HC16 1/20 0.67
GAA P10253 3/20 0.66
CYP2C9 P11712 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
MCOLN3 Q8TDD5 1/20 0.65
TSHR P16473 1/20 0.63
CYP2D6 P10635 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL735657 1.00 POLB (0.80) POLBPKMALDH1A1LMNASMN1; SMN2
SCHEMBL3830424 1.00 POLB (0.80) POLBPKMALDH1A1LMNASMN1; SMN2
SCHEMBL7469413 0.91 PKM (0.72) POLBPKMALDH1A1LMNASMN1; SMN2
SCHEMBL4526586 0.91 POLB (0.69) POLBPKMALDH1A1LMNASMN1; SMN2
SCHEMBL6805741 0.91 ALDH1A1 (0.81) POLBPKMALDH1A1LMNASMN1; SMN2
SCHEMBL1988224 0.91 ALDH1A1 (0.81) POLBPKMALDH1A1LMNASMN1; SMN2
SCHEMBL14470279 0.91 ALDH1A1 (0.75) POLBPKMALDH1A1LMNASMN1; SMN2
SCHEMBL20458879 0.89 POLB (0.67) POLBPKMALDH1A1LMNASMN1; SMN2
SCHEMBL5365907 0.89 POLB (0.67) POLBPKMALDH1A1LMNASMN1; SMN2
SCHEMBL20198535 0.89 POLB (0.67) POLBPKMALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US claimed
EP-1149877-B1 Decolorizable ink composition and ink jet printer using the ink composition RICOH KK (JP) 2003-06-11 EP disclosed
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US disclosed
US-20020175982-A1 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2002-11-28 US disclosed
EP-1149877-A1 Decolorizable ink composition and ink jet printer using the ink composition Ricoh Company, Ltd. (JP) 2001-10-31 EP disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed