Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12316782 | 0.81 | KMT2A (0.66) | KDM4ETSHRRECQLHSD17B10MEN1 | |
| SCHEMBL2751300 | 0.76 | ALDH1A1 (0.70) | KDM4EMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL5509544 | 0.76 | DHODH (0.57) | KDM4ETSHRRECQLHSD17B10MEN1 | |
| SCHEMBL4226856 | 0.76 | DGAT1 (0.69) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4226864 | 0.76 | DGAT1 (0.69) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4226860 | 0.76 | DGAT1 (0.69) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2835288 | 0.76 | GAA (0.73) | KDM4ETSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL9297476 | 0.74 | KMT2A (0.75) | KDM4EMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL8110954 | 0.74 | GAA (0.75) | KDM4ETSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL24496664 | 0.73 | GAA (0.69) | KDM4ETSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |