Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083278 | 0.71 | KDM4E (0.50) | ALDH1A1KDM4EALOX5TDP1LMNA | |
| SCHEMBL3824083 | 0.70 | KDM4E (0.56) | ALDH1A1KDM4EALOX5TDP1LMNA | |
| SCHEMBL14169017 | 0.68 | MAPT (0.42) | MAPTTSHRALDH1A1KDM4EPOLB | |
| SCHEMBL2083091 | 0.67 | MAPT (0.39) | MAPTTSHRALDH1A1KDM4EPOLB | |
| SCHEMBL16684141 | 0.67 | FAAH (0.35) | UGT2B7ALOX5CDC25A | |
| SCHEMBL10683475 | 0.67 | KDM4E (0.49) | TSHRALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL10686638 | 0.66 | KDM4E (0.48) | TSHRALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL8829499 | 0.66 | KDM4E (0.48) | TSHRALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL23014049 | 0.66 | FOLH1 (0.40) | TSHRALDH1A1POLBUGT2B7ALOX5 | |
| SCHEMBL8675518 | 0.66 | MAPT (0.43) | MAPTTSHRALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |