Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | BID | P55957 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827150 | 0.90 | AKR1B1 (0.61) | AKR1B1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL3623274 | 0.84 | AKR1B1 (0.59) | AKR1B1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL17078356 | 0.83 | MAPT (0.61) | AKR1B1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL17078364 | 0.83 | MAPT (0.61) | AKR1B1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL2517305 | 0.83 | MAPT (0.61) | AKR1B1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL16230472 | 0.83 | MAPT (0.61) | AKR1B1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL8009468 | 0.83 | MAPT (0.61) | AKR1B1HDAC3MAPK1ADRA1AHDAC4 | |
| Phenylbutanoic Acid SCHEMBL7703557 | 0.83 | HDAC1 (0.84) | AKR1B1HDAC3MAPK1ADRA1AHDAC4 | |
| Adipic Acid SCHEMBL5506667 | 0.80 | AKR1B1 (0.77) | AKR1B1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL7824940 | 0.80 | MPO (0.47) | AKR1B1HDAC3MAPK1ADRA1AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |