Sugi Predict

Sugi Predict / Compounds / SCHEMBL1827150

SCHEMBL1827150

SCHEMBL1827150

O=C(O)CCCc1ccccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AKR1B1 P15121 1/20 0.61
▸ HDAC3 O15379 1/20 0.59
▸ MAPK1 P28482 1/20 0.59
▸ ADRA1A P35348 1/20 0.59
▸ HDAC4 P56524 1/20 0.59
▸ SLC6A3 Q01959 1/20 0.59
▸ HDAC1 Q13547 1/20 0.59
▸ SMN1; SMN2 Q16637 1/20 0.59
▸ HDAC7 Q8WUI4 1/20 0.59
▸ HDAC2 Q92769 1/20 0.59
▸ HDAC10 Q969S8 1/20 0.59
▸ HDAC11 Q96DB2 1/20 0.59
▸ HDAC8 Q9BY41 1/20 0.59
▸ HDAC6 Q9UBN7 1/20 0.59
▸ HDAC9 Q9UKV0 1/20 0.59
▸ HDAC5 Q9UQL6 1/20 0.59
▸ MPO P05164 2/20 0.50
▸ TAAR1 Q96RJ0 1/20 0.50
▸ MAPT P10636 1/20 0.50
▸ RXFP1 Q9HBX9 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3623274 0.94 AKR1B1 (0.59) AKR1B1HDAC3MAPK1ADRA1AHDAC4
SCHEMBL17078356 0.92 MAPT (0.61) AKR1B1HDAC3MAPK1ADRA1AHDAC4
SCHEMBL8009468 0.92 MAPT (0.61) AKR1B1HDAC3MAPK1ADRA1AHDAC4
SCHEMBL2517305 0.92 MAPT (0.61) AKR1B1HDAC3MAPK1ADRA1AHDAC4
SCHEMBL17078364 0.92 MAPT (0.61) AKR1B1HDAC3MAPK1ADRA1AHDAC4
SCHEMBL16230472 0.92 MAPT (0.61) AKR1B1HDAC3MAPK1ADRA1AHDAC4
Phenylacetic Acid SCHEMBL7824936 0.90 AKR1B1 (0.59) AKR1B1HDAC3MAPK1ADRA1AHDAC4
SCHEMBL29373796 0.88 AKR1B1 (0.65) AKR1B1HDAC3MAPK1ADRA1AHDAC4
SCHEMBL35529 0.88 AKR1B1 (0.65) AKR1B1HDAC3MAPK1ADRA1AHDAC4
SCHEMBL7128255 0.88 AKR1B1 (0.65) AKR1B1HDAC3MAPK1ADRA1AHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110382699-A Method for producing polyhydroxyalkanoates using 2-hydroxyisocaproate-CoA transferase 韩国科学技术院 2019-10-25 — — CN claimed
CN-109593739-A Recombinate ketone acid reduction enzyme mutant, gene, engineering bacteria and its application 浙江工业大学 2019-04-09 — — CN claimed
CN-105777546-B A kind of preparation method of lisinopril intermediate 苏州引航生物科技有限公司 2018-01-09 — — CN claimed
CN-107311857-A (2 hydroxy phenyl) butyric acid of 4 hydroxyls of R 2 and its preparation and application 云南农业大学 2017-11-03 — — CN claimed
CN-106866402-A It is a kind of（R）The preparation method of the phenylbutyric acid of 2 hydroxyl 4 泰州市产品质量监督检验所 2017-06-20 — — CN claimed
CN-105777546-A Method for preparing lisinopril intermediate 苏州引航生物科技有限公司 2016-07-20 — — CN claimed
CN-105209390-A Rutile titanium dioxide nanoparticles and ordered acicular aggregates of same CRISTAL INORGANIC CHEMICALS SWITZERLAND LTD 2015-12-30 — — CN claimed
CN-102660470-A Sinorhizobium fredii and its application in producing chiral alpha-hydroxy acid by biologically splitting alpha-hydroxy acid raceme UNIV ZHEJIANG TECHNOLOGY 2012-09-12 — — CN claimed
CN-102660471-A Production of chiral alpha-hydroxy acid and its strain by using biological catalysis method UNIV ZHEJIANG TECHNOLOGY 2012-09-12 — — CN claimed
CN-101613279-B Method for preparing chiral compound of (R)-2-hydroxy-4-phenylbutyrate HANGZHOU FST PHARMACEUTICAL CO LTD 2012-06-06 — — CN claimed
CN-101613279-A The preparation method of chipal compounds (R)-2-hydroxy-4-phenyl ethyl butyrate HANGZHOU FST PHARMACEUTICALS C 2009-12-30 — — CN claimed
CN-100415892-C Process for microbial isomerization of alpha-hydroxycarboxylic acids BASF AG (DE) 2008-09-03 — — CN claimed
CN-1809642-A Process for microbial isomerization of alpha-hydroxycarboxylic acids BASF AG (DE) 2006-07-26 — — CN claimed
CN-1254536-C Novel(R)-2-hydroxy-3-phenylpropionate (D-phenyllactate) dehydrogenase and gene encoding the same MEIJI SEIKA KAISHA (JP) 2006-05-03 — — CN claimed
EP-1383741-A4 PROCESS FOR THE PREPARATION OF BENAZEPRIL RANBAXY LAB LTD (IN) 2006-01-04 — — EP claimed
US-20040152889-A1 Process for the preparation of benazepril RANBAXY LABORATORIES LIMITED (IN) 2004-08-05 — — US claimed
EP-1383741-A2 PROCESS FOR THE PREPARATION OF BENAZEPRIL RANBAXY LABORATORIES, LTD. (IN) 2004-01-28 — — EP claimed
WO-2002076375-A2 PROCESS FOR THE PREPARATION OF BENAZEPRIL RANBAXY LABORATORIES LIMITED (IN) 2002-10-03 — — WO claimed
CN-1322768-A Polyhydroxy alkanoate and process for producing them with microbe CANON KK (JP) 2001-11-21 — — CN claimed
US-6268463-B1 POLYPHENYLENE ETHERS WITH CARBOXY GROUPS GENERAL ELECTRIC COMPANY 2001-07-31 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152889-A1 Process for the preparation of benazepril ACE, ACE2, REN AKR1B1 89/4885HDAC3 215/4885MAPK1 2715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.