Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL953097 | 0.67 | ALDH1A1 (0.42) | ALDH1A1KMT2AHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL5848990 | 0.67 | ALDH1A1 (0.51) | ALDH1A1KMT2AHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL7373297 | 0.66 | POLB (0.39) | ALDH1A1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL20669696 | 0.66 | PIK3CG (0.51) | ALDH1A1KMT2AHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL683558 | 0.65 | THRB (0.44) | ALDH1A1KMT2AHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL335081 | 0.65 | KDM4E (0.60) | ALDH1A1KMT2AHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL683499 | 0.64 | POLB (0.38) | ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL7427855 | 0.63 | ALDH1A1 (0.36) | ALDH1A1KMT2AHSD17B10KDM4E | |
| SCHEMBL1613433 | 0.63 | HSD17B10 (0.36) | ALDH1A1KMT2AHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL17290828 | 0.63 | KDM4E (0.44) | ALDH1A1KMT2AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433855-B1 | N- and O-substituted aminophenol derivatives, intermediates for their preparation, their use as hydrolase substrates, a corresponding assay and diagnostic agents | ROCHE DIAGNOSTICS GMBH (DE) | 2001-03-07 | — | — | EP | disclosed |
| EP-0433854-B1 | 3-Aminopyrazolo heterocycles, their use for the determination of hydrogen peroxide, hydrogen peroxide forming systems, peroxidase, peroxidant active substances or electron rich aromatic compounds, corresponding determination process and agents | BOEHRINGER MANNHEIM GMBH (DE) | 1997-06-18 | — | — | EP | disclosed |
| US-5457200-A | Oxidative coupling reactions for determination of hydrogen peroxide | BOEHRINGER MANNHEIM (DE) | 1995-10-10 | — | — | US | disclosed |
| US-5334505-A | For colorimetric determination of hydrolases | BOEHRINGER MANNHEIM GMBH (DE) | 1994-08-02 | — | — | US | disclosed |
| US-5234818-A | Detecting hydrogen peroxide, peroxidase by oxidative coupling with electron-rich aromatic compound | BOEHRINGER MANNHEIM GMBH (DE) | 1993-08-10 | — | — | US | disclosed |
| EP-0433854-A2 | 3-Aminopyrazolo heterocycles, their use for the determination of hydrogen peroxide, hydrogen peroxide forming systems, peroxidase, peroxidant active substances or electron rich aromatic compounds, corresponding determination process and agents | Roche Diagnostics GmbH (DE) | 1991-06-26 | — | — | EP | disclosed |
| EP-0433855-A2 | N- and O-substituted aminophenol derivatives, intermediates for their preparation, their use as hydrolase substrates, a corresponding assay and diagnostic agents | Roche Diagnostics GmbH (DE) | 1991-06-26 | — | — | EP | disclosed |