Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825171 | 1.00 | THRB (0.39) | THRBTSHRTP53EGLN1EGLN3 | |
| SCHEMBL9187017 | 0.85 | TSHR (0.42) | TSHRTP53EGLN1EGLN3LMNA | |
| SCHEMBL16178793 | 0.79 | THRB (0.46) | THRBTSHRTP53EGLN1EGLN3 | |
| SCHEMBL8830567 | 0.79 | THRB (0.46) | THRBTSHRTP53EGLN1EGLN3 | |
| SCHEMBL32685382 | 0.79 | THRB (0.46) | THRBTSHRTP53EGLN1EGLN3 | |
| SCHEMBL28564049 | 0.79 | THRB (0.46) | THRBTSHRTP53EGLN1EGLN3 | |
| SCHEMBL5704732 | 0.74 | TSHR (0.36) | THRBTSHRTP53EGLN1EGLN3 | |
| SCHEMBL7812907 | 0.74 | TSHR (0.36) | THRBTSHRTP53EGLN1EGLN3 | |
| Perflubutane SCHEMBL5248912 | 0.72 | LMNA (0.59) | THRBTSHRTP53EGLN1EGLN3 | |
| SCHEMBL899316 | 0.72 | TSHR (0.44) | THRBTSHRTP53EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |