Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PDE8B | O95263 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7830535 | 0.94 | ALOX15 (0.41) | ALOX15L3MBTL1AKR1C3POLBMAPT | |
| SCHEMBL7827258 | 0.93 | ALOX15 (0.42) | ALOX15L3MBTL1NPC1CYP1A2CYP3A4 | |
| SCHEMBL7816184 | 0.90 | CYP19A1 (0.44) | ALOX15L3MBTL1POLBMAPTKMT2A | |
| SCHEMBL7829292 | 0.90 | ALOX15 (0.42) | ALOX15L3MBTL1AKR1C3POLBMAPT | |
| SCHEMBL7830851 | 0.89 | HPGD (0.50) | ALOX15L3MBTL1CYP1A2CYP3A4AKR1C3 | |
| SCHEMBL7815565 | 0.88 | ALOX15 (0.40) | ALOX15L3MBTL1AKR1C3POLBMAPT | |
| SCHEMBL7826331 | 0.88 | MAPT (0.43) | ALOX15L3MBTL1CYP1A2CYP3A4AKR1C3 | |
| SCHEMBL5514056 | 0.88 | LMNA (0.46) | ALOX15L3MBTL1NPC1CYP1A2CYP2D6 | |
| SCHEMBL7824951 | 0.87 | PTGER4 (0.42) | ALOX15L3MBTL1AKR1C3POLBMAPT | |
| SCHEMBL7816277 | 0.87 | POLB (0.43) | ALOX15L3MBTL1AKR1C3POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |