Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Disofenin SCHEMBL135703 | 0.81 | TDP1 (0.64) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| Disofenin SCHEMBL29687882 | 0.80 | TDP1 (0.62) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL9679857 | 0.73 | SOAT2 (0.57) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL29540672 | 0.72 | MCL1 (0.72) | ALOX15TSHRTDP1SMN1; SMN2MCL1 | |
| SCHEMBL118785 | 0.72 | MCL1 (0.72) | ALOX15TSHRTDP1SMN1; SMN2MCL1 | |
| Acetic Acid SCHEMBL28287287 | 0.71 | MCL1 (0.71) | ALOX15TSHRTDP1SMN1; SMN2MCL1 | |
| SCHEMBL28808000 | 0.71 | MCL1 (0.70) | ALOX15TSHRTDP1SMN1; SMN2MCL1 | |
| Hydrochloric Acid SCHEMBL8437530 | 0.71 | MCL1 (0.70) | ALOX15TSHRTDP1SMN1; SMN2MCL1 | |
| SCHEMBL9491944 | 0.70 | LMNA (0.65) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL9679656 | 0.68 | SOAT2 (0.60) | TDP1SMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |