Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 11/20 | 0.38 |
| ▸ | GABRD | O14764 | 11/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 11/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 11/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 11/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 11/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 11/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 11/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 11/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 11/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 11/20 | 0.38 |
| ▸ | GABRE | P78334 | 11/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 11/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 11/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 11/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055915 | 0.92 | MAPT (0.42) | LMNAHPGDKDM4EMAPTTP53 | |
| SCHEMBL4202649 | 0.88 | CA12 (0.41) | LMNAHPGDKDM4EMAPTGABRP | |
| SCHEMBL27462 | 0.88 | CA12 (0.41) | LMNAHPGDKDM4EMAPTGABRP | |
| Hydrochloric Acid SCHEMBL1734541 | 0.88 | CA12 (0.40) | LMNAHPGDKDM4EMAPTGABRP | |
| SCHEMBL6055900 | 0.87 | GABRP (0.37) | LMNAHPGDKDM4EMAPTGABRP | |
| SCHEMBL6055908 | 0.85 | GABRB3 (0.40) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7819225 | 0.83 | GABRP (0.41) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL6055777 | 0.83 | CA12 (0.40) | LMNAHPGDKDM4EMAPTGABRP | |
| SCHEMBL6055828 | 0.82 | GABRP (0.41) | LMNAKDM4EMAPTGABRPGABRD | |
| SCHEMBL6055715 | 0.81 | GAA (0.42) | LMNAHPGDKDM4EMAPTGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236938-A | Pesticidal 1-aryl-5-(substituted alkylideneimino)pyrazoles | RHONE-POULENC INC. (US) | 1993-08-17 | — | — | US | claimed |
| EP-0511845-B1 | Pesticidal 1-aryl-5-(substituted alkylideneimino)-pyrazoles | AVENTIS CROPSCIENCE SA (FR) | 2001-10-31 | — | — | EP | disclosed |