SCHEMBL7825833

SCHEMBL7825833

O=C(O)C(=O)OC1CCNc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F12 P00748 18/20 0.35
ALDH1A1 P00352 1/20 0.35
F2 P00734 2/20 0.34
HDAC1 Q13547 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7835340 0.91 ALDH1A1 (0.33) F12ALDH1A1F2
SCHEMBL28039980 0.84 POLB (0.45) F12
SCHEMBL28639323 0.81 F12 (0.36) F12F2HDAC1
SCHEMBL10565873 0.79 F12 (0.40) F12F2
SCHEMBL13315859 0.74 HTR2C (0.39) F12ALDH1A1
SCHEMBL30899479 0.72 ALDH1A1 (0.54) F12ALDH1A1F2
SCHEMBL30020668 0.72 ALDH1A1 (0.54) F12ALDH1A1F2
SCHEMBL768982 0.72 ALDH1A1 (0.54) F12ALDH1A1F2
SCHEMBL19457862 0.69 F12 (0.37) F12ALDH1A1F2
SCHEMBL1872257 0.69 BDKRB1 (0.46) HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1090631-C Heterocyclic compound, preparation process thereof and medicinal composition containing same SEUER LAB (FR) 2002-09-11 CN disclosed
EP-1070054-A1 AMINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS SOMATOSTATIN RECEPTOR ANTAGONISTS OR AGONISTS Takeda Chemical Industries, Ltd. (JP) 2001-01-24 EP disclosed
WO-1999052875-A1 AMINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS SOMATOSTATIN RECEPTOR ANTAGONISTS OR AGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-10-21 WO disclosed
CN-1206712-A Heterocyclic compound, preparation process thereof and medicinal composition containing same ADIR (FR) 1999-02-03 CN disclosed