Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 6/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | HNF4A | P41235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825833 | 0.91 | F12 (0.35) | ALDH1A1F12F2 | |
| SCHEMBL28039980 | 0.76 | POLB (0.45) | F12POLB | |
| SCHEMBL4867338 | 0.76 | SLC6A2 (0.42) | — | |
| SCHEMBL7377538 | 0.74 | ALDH1A1 (0.51) | ALDH1A1KCNH2F12POLB | |
| SCHEMBL28639323 | 0.73 | F12 (0.36) | F12F2PTGDR2 | |
| Hydrochloric Acid SCHEMBL3264285 | 0.72 | LTA4H (0.33) | KCNH2 | |
| SCHEMBL3260672 | 0.72 | REN (0.35) | F12F2 | |
| SCHEMBL10565873 | 0.71 | F12 (0.40) | F12F2 | |
| SCHEMBL1652868 | 0.70 | BCHE (0.34) | ALDH1A1F12 | |
| SCHEMBL5301574 | 0.70 | F12 (0.41) | ALDH1A1KCNH2F12POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070054-A1 | AMINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS SOMATOSTATIN RECEPTOR ANTAGONISTS OR AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052875-A1 | AMINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS SOMATOSTATIN RECEPTOR ANTAGONISTS OR AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-21 | — | — | WO | disclosed |