Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.34 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817212 | 0.74 | AOC3 (0.40) | AOC3CXCR1CXCR2NPC1RAB9A | |
| SCHEMBL13516155 | 0.65 | ALDH1A1 (0.46) | AOC3TARBP2NPC1RAB9AMAPT | |
| SCHEMBL11770285 | 0.64 | TARBP2 (0.44) | AOC3TARBP2NPC1RAB9AMAPT | |
| SCHEMBL13516225 | 0.63 | KDM4E (0.40) | AOC3TARBP2NPSR1 | |
| SCHEMBL6012205 | 0.63 | PREP (0.38) | PREP | |
| SCHEMBL4882804 | 0.62 | PREP (0.50) | PREPTARBP2NPC1RAB9ANPSR1 | |
| SCHEMBL10446374 | 0.62 | AOC3 (0.42) | AOC3NPC1RAB9ANPSR1 | |
| SCHEMBL13516234 | 0.61 | KMT2A (0.55) | AOC3TARBP2NPC1RAB9AMAPT | |
| SCHEMBL1027211 | 0.60 | AOC3 (0.43) | AOC3NPC1RAB9ANPSR1MAPT | |
| SCHEMBL6341931 | 0.60 | AOC3 (0.43) | AOC3NPC1RAB9ANPSR1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809643-B1 | SYNTHESIS OF (+)-PANCRATISTATIN | VIRGINIA TECH INTELL PROP (US) | 2001-10-17 | — | — | EP | disclosed |
| US-5627280-A | Synthesis of (+)-pancratistatin | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1997-05-06 | — | — | US | disclosed |