SCHEMBL6012205

SCHEMBL6012205

CC(C)(C)[Si](C)(C)Oc1c2ccc(C(=O)O)c1OC2

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PREP P48147 3/20 0.38
PRF1 P14222 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL433142 0.75 CXCR2 (0.43) PREP
SCHEMBL7598320 0.69 MAPK1 (0.49)
SCHEMBL7026132 0.69 WDR5 (0.50)
SCHEMBL20390042 0.67 LCK (0.44)
SCHEMBL12231831 0.66 PREP (0.30) PREP
SCHEMBL7557301 0.65 KDM4E (0.51)
SCHEMBL30872150 0.65 KDM4E (0.51)
SCHEMBL4753702 0.65 CA12 (0.46) PREP
SCHEMBL30594486 0.64 HTT (0.45)
SCHEMBL9487230 0.64 ALDH1A1 (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1735621-A2 NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES Giri, Brij P. (US) 2006-12-27 EP disclosed
WO-2006073424-A9 NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES GIRI BRIJ P (US) 2006-08-24 WO disclosed
WO-2006073424-A2 NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES GIRI BRIJ P (US) 2006-07-13 WO disclosed