Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYCS | P99999 | 2/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298629 | 0.81 | LMNA (0.51) | ALDH1A1POLBKMT2ALMNASMN1; SMN2 | |
| SCHEMBL5399079 | 0.79 | ALDH1A1 (0.47) | TTRALDH1A1RXRARXRBTOP1 | |
| SCHEMBL6465905 | 0.75 | ALDH1A1 (0.75) | TTRALDH1A1RXRARXRBTOP1 | |
| SCHEMBL6464286 | 0.72 | KMT2A (0.50) | TTRALDH1A1TOP1POLBKMT2A | |
| SCHEMBL24733376 | 0.70 | ALDH1A1 (0.58) | TTRALDH1A1RXRARXRBPOLB | |
| SCHEMBL29558263 | 0.70 | ALDH1A1 (0.58) | TTRALDH1A1RXRARXRBPOLB | |
| SCHEMBL29624164 | 0.70 | ALDH1A1 (0.58) | TTRALDH1A1RXRARXRBPOLB | |
| SCHEMBL2219516 | 0.70 | KDM4E (0.54) | ALDH1A1POLBKMT2ALMNAKDM4E | |
| SCHEMBL11219580 | 0.70 | TSHR (0.71) | TTRALDH1A1RXRARXRBTOP1 | |
| SCHEMBL5401610 | 0.68 | TTR (0.49) | TTRALDH1A1RXRARXRBTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |