Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 6/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6360371 | 0.82 | ALDH1A1 (0.46) | ALDH1A1GAASMN1; SMN2KDM4EPARP1 | |
| SCHEMBL7836794 | 0.80 | ALDH1A1 (0.54) | ALDH1A1GAASMN1; SMN2KDM4EPARP1 | |
| SCHEMBL9868222 | 0.75 | ALDH1A1 (0.40) | ALDH1A1GAASMN1; SMN2KDM4EPARP1 | |
| SCHEMBL4230107 | 0.75 | PARP1 (0.54) | ALDH1A1GAASMN1; SMN2KDM4EPARP1 | |
| SCHEMBL15667350 | 0.74 | PARP1 (0.43) | ALDH1A1GAASMN1; SMN2KDM4EPARP1 | |
| SCHEMBL15667117 | 0.74 | PARP1 (0.43) | ALDH1A1GAASMN1; SMN2KDM4EPARP1 | |
| SCHEMBL15667115 | 0.74 | PARP1 (0.43) | ALDH1A1GAASMN1; SMN2KDM4EPARP1 | |
| SCHEMBL15758217 | 0.74 | PARP1 (0.40) | ALDH1A1SMN1; SMN2PARP1BRD4TDP1 | |
| SCHEMBL28821790 | 0.73 | PARP1 (0.43) | ALDH1A1GAASMN1; SMN2PARP1BRD4 | |
| SCHEMBL28028043 | 0.73 | PARP1 (0.43) | ALDH1A1GAASMN1; SMN2PARP1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826684-B1 | PIPERIDINE DERIVATIVES | HISAMITSU PHARMACEUTICAL CO (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5886011-A | TACHYKININ UNDECAPEPTIDE ANTAGONIST, USEFUL FOR TREATING ASTHMA, OR REMEDY FOR DISEASES ASSOCIATED WITH CENTRAL NERVOUS SYSTEM, DIGESTIVE SYSTEM AND CIRULATORY STYSTEM, AND VARIETY OF PAINS OR INFLAMMATION | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0826684-A1 | PIPERIDINE DERIVATIVES | Hisamitsu Pharmaceutical Co., Inc. (JP) | 1998-03-04 | — | — | EP | disclosed |