Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 4/20 | 0.39 |
| ▸ | EDNRA | P25101 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826524 | 0.93 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1HTTRAB9ANPC1 | |
| SCHEMBL7068358 | 0.87 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1HTTRAB9ANPC1 | |
| SCHEMBL7828200 | 0.86 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTRAB9ANPC1 | |
| SCHEMBL7817828 | 0.86 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTRAB9ANPC1 | |
| SCHEMBL7823695 | 0.86 | EDNRB (0.43) | ALDH1A1L3MBTL1HTTEDNRBEDNRA | |
| SCHEMBL7831845 | 0.84 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1HTTRAB9ANPC1 | |
| SCHEMBL7827165 | 0.83 | SLC16A3 (0.44) | ALDH1A1L3MBTL1HTTRAB9ANPC1 | |
| SCHEMBL7828476 | 0.83 | EDNRB (0.43) | ALDH1A1L3MBTL1HTTEDNRBEDNRA | |
| SCHEMBL7828607 | 0.82 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1HTTRAB9ANPC1 | |
| SCHEMBL7828049 | 0.82 | EDNRB (0.48) | ALDH1A1L3MBTL1HTTEDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811001-B1 | BENZOTHIAZINE DIOXIDES AS ENDOTHELIN ANTAGONISTS | WARNER LAMBERT CO (US) | 2001-10-31 | — | — | EP | claimed |