Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.41 |
| ▸ | SLC9A2 | Q9UBY0 | 2/20 | 0.41 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | AOC2 | O75106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7825948 | 0.84 | HTR7 (0.40) | SLC9A1SLC9A2SLC9A3MRGPRX4AOC2 | |
| SCHEMBL7826496 | 0.83 | SLC9A1 (0.43) | SLC9A1SLC9A2SLC9A3AOC2 | |
| SCHEMBL29406734 | 0.83 | SLC9A1 (0.43) | SLC9A1SLC9A2SLC9A3AOC2 | |
| SCHEMBL1388039 | 0.80 | VHL (0.40) | SLC9A1SLC9A2SLC9A3MRGPRX4AOC2 | |
| Hydrochloric Acid SCHEMBL7826502 | 0.79 | VHL (0.39) | SLC9A1SLC9A2SLC9A3MRGPRX4AOC2 | |
| SCHEMBL1388080 | 0.78 | SLC9A1 (0.43) | SLC9A1SLC9A2SLC9A3AOC2 | |
| SCHEMBL7822725 | 0.78 | SLC9A1 (0.49) | SLC9A1SLC9A2SLC9A3 | |
| SCHEMBL7822636 | 0.78 | SLC9A1 (0.40) | SLC9A1SLC9A2 | |
| Hydrochloric Acid SCHEMBL7822462 | 0.77 | SLC9A1 (0.36) | SLC9A1SLC9A2SLC9A3MRGPRX4AOC2 | |
| Hydrochloric Acid SCHEMBL27383698 | 0.77 | SLC9A1 (0.36) | SLC9A1SLC9A2SLC9A3MRGPRX4AOC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699185-B1 | GUANIDINE DERIVATIVES AS INHIBITORS OF Na+ /H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| WO-1994026709-A1 | GUANIDINE DERIVATIVES AS INHIBITORS OF Na+/H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |