Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.57 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | ARG2 | P78540 | 4/20 | 0.46 |
| ▸ | ARG1 | P05089 | 3/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450798 | 1.00 | OTC (0.57) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL450041 | 0.95 | OTC (0.63) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL5548101 | 0.95 | OTC (0.63) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL22689763 | 0.86 | OTC (0.54) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL22689846 | 0.85 | OTC (0.53) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL6183879 | 0.84 | OTC (0.58) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL14682811 | 0.84 | OTC (0.58) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL18350239 | 0.84 | OTC (0.58) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL6672850 | 0.84 | OTC (0.58) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL5973446 | 0.84 | OTC (0.58) | OTCGSRARG2ARG1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105276-A1 | COMBINATION OF POLYAMINE PATHWAY INHIBITOR DRUG AND PROLINE/ARGININE DIET RESTRICTION | Universität Zürich (CH) | 2024-05-23 | — | — | WO | disclosed |
| CN-118043053-A | Methods of treating cancer | 福宏治疗公司 | 2024-05-14 | — | — | CN | disclosed |
| WO-2018222975-A1 | METHODS FOR THE TREATMENT OF CANCER | RGENIX, INC. (US) | 2018-12-06 | — | — | WO | disclosed |
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |