SCHEMBL450041

SCHEMBL450041

N[C@@H](CCCNC(=O)CI)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OTC P00480 1/20 0.63
GSR P00390 2/20 0.47
DDAH1 O94760 3/20 0.47
NOD1 Q9Y239 2/20 0.46
ARG2 P78540 4/20 0.43
ARG1 P05089 3/20 0.43
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
NOS2 P35228 2/20 0.42
GLA P06280 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
APEX1 P27695 1/20 0.42
GRM8 O00222 1/20 0.41
GRM6 O15303 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIK1 P39086 1/20 0.41
GRM5 P41594 1/20 0.41
GRIA1 P42261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5548101 1.00 OTC (0.63) OTCGSRDDAH1NOD1ARG2
SCHEMBL450798 0.95 OTC (0.57) OTCGSRDDAH1NOD1ARG2
SCHEMBL7826522 0.95 OTC (0.57) OTCGSRDDAH1NOD1ARG2
SCHEMBL25186309 0.83 OTC (0.65) OTCGSRDDAH1NOD1ARG2
SCHEMBL13043221 0.83 OTC (0.65) OTCGSRDDAH1NOD1ARG2
SCHEMBL25186310 0.83 OTC (0.65) OTCGSRDDAH1NOD1ARG2
SCHEMBL2237070 0.81 OTC (0.63) OTCGSRDDAH1NOD1ARG2
SCHEMBL2237074 0.81 OTC (0.63) OTCGSRDDAH1NOD1ARG2
SCHEMBL22689763 0.81 OTC (0.54) OTCGSRDDAH1NOD1ARG2
SCHEMBL2236948 0.80 OTC (0.61) OTCGSRDDAH1NOD1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117521484-A Sea surface wind speed inversion method and equipment based on single left-hand circularly polarized antenna 中国气象局气象探测中心 2024-02-06 CN claimed
EP-3696281-A1 ARGINASE AS BIOMARKER AND DRUG TARGET FOR PCOS Johann Wolfgang Goethe-Universität Frankfurt am Main (DE) 2020-08-19 EP claimed
US-20150335663-A1 Pharmaceutical Composition Having Synergistic Action Of Direct Catalase Inhibitors And Modulators Of NO Metabolism Or Of Extracellular Superoxide Anion Production Which Lead To Catalase Destruction UNIVERSITAETSKLINIKUM FREIBURG (DE) 2015-11-26 US claimed
EP-2863907-A1 PHARMACEUTICAL COMPOSITION HAVING SYNERGISTIC ACTION OF DIRECT CATALASE INHIBITORS AND MODULATORS OF NO METABOLISM OR OF EXTRACELLULAR SUPEROXIDE ANION PRODUCTION WHICH LEAD TO CATALASE DESTRUCTION Universitätsklinikum Freiburg (DE) 2015-04-29 EP claimed
WO-2014001183-A1 PHARMACEUTICAL COMPOSITION HAVING SYNERGISTIC ACTION OF DIRECT CATALASE INHIBITORS AND MODULATORS OF NO METABOLISM OR OF EXTRACELLULAR SUPEROXIDE ANION PRODUCTION WHICH LEAD TO CATALASE DESTRUCTION Universitätsklinikum Freiburg (DE) 2014-01-03 WO claimed
JP-4723476-B2 2011-07-13 JP claimed
EP-1863431-A1 HAIR AND/OR EYELASH CARE COMPOSITION CONTAINING AMINEXIL IN COMBINATION WITH AN AGENT FOR PROMOTING THE NO PRODUCTION AND USES THEREOF L'Oréal (FR) 2007-12-12 EP claimed
EP-1596854-A4 TREATMENT OF CONDITIONS ASSOCIATED WITH DECREASED NITRIC OXIDE BIOAVAILABILITY, INCLUDING ELEVATED ARGINASE CONDITIONS CHILDRENS HOSP & RES CT OAK (US) 2007-06-06 EP claimed
WO-2006097359-A1 HAIR AND/OR EYELASH CARE COMPOSITION CONTAINING AMINEXIL IN COMBINATION WITH AN AGENT FOR PROMOTING THE NO PRODUCTION AND USES THEREOF L'ORÉAL (FR) 2006-09-21 WO claimed
JP-2006518387-A 2006-08-10 JP claimed
EP-1596854-A2 TREATMENT OF CONDITIONS ASSOCIATED WITH DECREASED NITRIC OXIDE BIOAVAILABILITY, INCLUDING ELEVATED ARGINASE CONDITIONS Children's Hospital & Research Center at Oakland (US) 2005-11-23 EP claimed
US-20050158401-A1 Treatment and diagnosis of conditions associated with elevated arginase activity NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-07-21 US claimed
WO-2004073623-A9 TREATMENT OF CONDITIONS ASSOCIATED WITH DECREASED NITRIC OXIDE BIOAVAILABILITY, INCLUDING ELEVATED ARGINASE CONDITIONS CHILDRENS HOSP & RES CT OAK (US) 2005-01-27 WO claimed
WO-2004073623-A2 TREATMENT OF CONDITIONS ASSOCIATED WITH DECREASED NITRIC OXIDE BIOAVAILABILITY, INCLUDING ELEVATED ARGINASE CONDITIONS CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) 2004-09-02 WO claimed
US-12569445-B2 Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof HALOZYME HYPERCON, INC. (US) 2026-03-10 US disclosed
US-12558323-B2 Particle formation and morphology ELEKTROFI, INC. (US) 2026-02-24 US disclosed
US-20260007615-A1 PARTICLES COMPRISING A THERAPEUTIC OR DIAGNOSTIC AGENT AND SUSPENSIONS AND METHODS OF USE THEREOF ELEKTROFI INC (US) 2026-01-08 US disclosed
WO-2004073623-A2 TREATMENT OF CONDITIONS ASSOCIATED WITH DECREASED NITRIC OXIDE BIOAVAILABILITY, INCLUDING ELEVATED ARGINASE CONDITIONS CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) 2004-09-02 WO disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569445-B2 Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof ALB, S100P, S100A8 OTC 1834/4885GSR 4809/4885DDAH1 4844/4885
US-12558323-B2 Particle formation and morphology CD63, EXOSC10, EPCAM OTC 3506/4885GSR 4614/4885DDAH1 4713/4885
US-20260007615-A1 PARTICLES COMPRISING A THERAPEUTIC OR DIAGNOSTIC AGENT AND SUSPENSIONS AND METHODS OF USE THEREOF FLNB, FLNA, FUS OTC 2070/4885GSR 4117/4885DDAH1 4474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.