Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.46 |
| ▸ | FNTA | P49354 | 3/20 | 0.37 |
| ▸ | FNTB | P49356 | 3/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850296 | 0.79 | HRH3 (0.40) | CYP19A1FNTAFNTBPGGT1BHRH3 | |
| SCHEMBL7826548 | 0.74 | FNTA (0.44) | CYP19A1FNTAFNTBPGGT1BHRH3 | |
| Hydrochloric Acid SCHEMBL7834168 | 0.74 | FNTA (0.44) | CYP19A1FNTAFNTBPGGT1BHRH3 | |
| SCHEMBL5552211 | 0.71 | HRH3 (0.41) | CYP19A1FNTAFNTBPGGT1BHRH3 | |
| SCHEMBL8009894 | 0.67 | CYP19A1 (0.45) | CYP19A1FNTAFNTBHRH3 | |
| SCHEMBL7845880 | 0.67 | FNTA (0.49) | CYP19A1FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7840097 | 0.67 | FNTA (0.48) | CYP19A1FNTAFNTBPGGT1B | |
| SCHEMBL7703567 | 0.66 | HRH3 (0.55) | CYP19A1HRH3CPA1 | |
| SCHEMBL7703563 | 0.66 | HRH3 (0.55) | CYP19A1HRH3CPA1 | |
| SCHEMBL7053727 | 0.66 | CPA1 (0.71) | CYP19A1HRH3CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891349-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-01-24 | — | — | EP | claimed |
| EP-0891349-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036888-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | claimed |
| EP-0891349-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-01-24 | — | — | EP | disclosed |
| EP-0891349-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036888-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |