Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30451351 | 0.88 | RAB9A (0.73) | RAB9AMAPTGAAALDH1A1LMNA | |
| SCHEMBL16140720 | 0.85 | RAB9A (0.78) | RAB9AMAPTGAAALDH1A1LMNA | |
| SCHEMBL1307557 | 0.84 | TP53 (0.67) | RAB9AMAPTGAAALDH1A1LMNA | |
| SCHEMBL24252964 | 0.83 | MAPT (0.66) | RAB9AMAPTGAAALDH1A1LMNA | |
| SCHEMBL2700280 | 0.81 | CYP1A2 (0.77) | RAB9AMAPTGAAALDH1A1KDM4E | |
| SCHEMBL21089188 | 0.81 | MAPT (0.74) | RAB9AMAPTGAAALDH1A1LMNA | |
| SCHEMBL22113944 | 0.79 | KMT2A (0.58) | RAB9AMAPTGAAALDH1A1LMNA | |
| SCHEMBL16138819 | 0.79 | ALDH1A1 (0.51) | RAB9AMAPTGAAALDH1A1LMNA | |
| SCHEMBL17407572 | 0.79 | KMT2A (0.55) | RAB9AMAPTGAAALDH1A1LMNA | |
| SCHEMBL22007921 | 0.78 | MEN1 (0.64) | RAB9AMAPTALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |