Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7823933 | 0.91 | MAPT (0.48) | MAPTRAB9ANPSR1JAK2JAK1 | |
| SCHEMBL7826791 | 0.87 | MAPT (0.44) | MAPTRAB9ANPSR1MEN1KMT2A | |
| SCHEMBL7831960 | 0.84 | GPR35 (0.43) | MAPTNPSR1MEN1KMT2AKDM4E | |
| SCHEMBL7825581 | 0.84 | MAPT (0.41) | MAPTRAB9ANPSR1MEN1KMT2A | |
| SCHEMBL7831446 | 0.83 | MAPT (0.41) | MAPTRAB9ANPSR1MEN1KMT2A | |
| SCHEMBL7832094 | 0.83 | ALDH1A1 (0.40) | MAPTRAB9ANPSR1MEN1KMT2A | |
| SCHEMBL7827801 | 0.83 | MAPT (0.42) | MAPTRAB9ANPSR1KDM4EALDH1A1 | |
| SCHEMBL7831953 | 0.83 | ALDH1A1 (0.46) | L3MBTL1MAPTRAB9ANPSR1MEN1 | |
| SCHEMBL7827661 | 0.82 | TP53 (0.43) | MAPTRAB9ANPSR1TP53TAS1R3 | |
| SCHEMBL7815986 | 0.81 | MAPT (0.39) | MAPTRAB9ANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-B1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5858995-A | ADMINISTERING TO HUMANS AND ANIMALS IN THE TREATMENT OF DISEASES CAUSED BY ABNORMAL BONE METABOLISM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |