Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217193 | 0.83 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL4192173 | 0.83 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL9679416 | 0.81 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL22292113 | 0.80 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2A | |
| SCHEMBL17336057 | 0.80 | MEN1 (0.45) | ALDH1A1MEN1KMT2A | |
| SCHEMBL30781661 | 0.77 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL9724464 | 0.77 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL14278867 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL14233382 | 0.75 | KMT2A (0.51) | ALDH1A1MEN1KMT2A | |
| SCHEMBL820099 | 0.75 | KMT2A (0.51) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161430-A2 | EPOTHILON DERIVATIVES, METHOD FOR THE PRODUCTION AND THE USE THEREOF AS PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000047584-A2 | EPOTHILON DERIVATIVES, METHOD FOR THE PRODUCTION AND THE USE THEREOF AS PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-08-17 | — | — | WO | disclosed |