SCHEMBL820099

SCHEMBL820099

OCCCCOC1CCCCO1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.51
MEN1 O00255 1/20 0.51
KDM4C Q9H3R0 1/20 0.40
ALDH1A1 P00352 8/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
POLB P06746 1/20 0.37
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
RECQL P46063 2/20 0.35
KDM4E B2RXH2 3/20 0.35
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14233382 1.00 KMT2A (0.51) KMT2AMEN1KDM4CALDH1A1L3MBTL1
SCHEMBL9527531 0.98 KMT2A (0.54) KMT2AMEN1KDM4CALDH1A1L3MBTL1
SCHEMBL2913896 0.98 KMT2A (0.54) KMT2AMEN1KDM4CALDH1A1L3MBTL1
SCHEMBL15151056 0.98 KMT2A (0.54) KMT2AMEN1KDM4CALDH1A1L3MBTL1
SCHEMBL18364935 0.98 KMT2A (0.54) KMT2AMEN1KDM4CALDH1A1L3MBTL1
SCHEMBL6906651 0.98 KMT2A (0.54) KMT2AMEN1KDM4CALDH1A1L3MBTL1
SCHEMBL7057539 0.98 KMT2A (0.54) KMT2AMEN1KDM4CALDH1A1L3MBTL1
SCHEMBL8854257 0.98 KMT2A (0.54) KMT2AMEN1KDM4CALDH1A1L3MBTL1
SCHEMBL8498418 0.98 KMT2A (0.54) KMT2AMEN1KDM4CALDH1A1L3MBTL1
SCHEMBL20128999 0.96 KMT2A (0.49) KMT2AMEN1KDM4CALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109678818-B Method for synthesizing aggregation pheromone (E) -cis-6,7-epoxy-2-nonenal of taurus communis 常州大学 2020-06-16 CN claimed
WO-2024130095-A9 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-08-02 WO disclosed
WO-2024130095-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-06-20 WO disclosed
US-11912699-B2 Tau-protein targeting compounds and associated ARVINAS OPERATIONS, INC. (US) 2024-02-27 US disclosed
US-20230212103-A1 POLYETHYLENE GLYCOL DERIVATIVE AND USE THEREOF HANMI PHARM. CO., LTD. (KR) 2023-07-06 US disclosed
US-11485812-B2 Pyranoquinazoline derivatives and naphthopyran derivatives KANTO KAGAKU KABUSHIKI KAISHA (JP) 2022-11-01 US disclosed
US-10792361-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2020-10-06 US disclosed
US-10729775-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2020-08-04 US disclosed
CN-109678818-B Method for synthesizing aggregation pheromone (E) -cis-6,7-epoxy-2-nonenal of taurus communis 常州大学 2020-06-16 CN disclosed
US-20200131193-A1 PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES KANTO KAGAKU KABUSHIKI KAISHA (JP) 2020-04-30 US disclosed
EP-0465835-A1 Anionic living polymers, their derivatives and composition comprising them DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-01-15 EP disclosed
US-5053548-A Containing hydroxy substituents; nervous system disorders OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) 1991-10-01 US disclosed
US-4977267-A ANTISECRETORY AGENT FUJIREBIO KABUSHIKI KAISHA (JP) 1990-12-11 US disclosed
EP-0382213-A2 Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed
US-4912101-A Containing a secondary amide, suflur group and a furan ring FUJIREBIO KABUSHIKI KAISHA (JP) 1990-03-27 US disclosed
US-4849436-A TREATMENT OF CARDIOVASCULAR DISORDERS NELSON RESEARCH & DEVELOPMENT CO. (US) 1989-07-18 US disclosed
EP-0282077-A2 Pyridyloxy derivatives FUJIREBIO KABUSHIKI KAISHA (JP) 1988-09-14 EP disclosed
EP-0259462-A1 1,4-DIHYDROPYRIDINES Whitby Research Incorporated (US) 1988-03-16 EP disclosed
WO-1987005512-A1 1,4-DIHYDROPYRIDINES NELSON RESEARCH AND DEVELOPMENT COMPANY (US) 1987-09-24 WO disclosed
EP-0183177-A1 Unsaturated fatty acid derivatives and their production SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1986-06-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912699-B2 Tau-protein targeting compounds and associated MAPT, VHL, CRBN KMT2A 1250/4885MEN1 1944/4885KDM4C 2111/4885
US-11485812-B2 Pyranoquinazoline derivatives and naphthopyran derivatives PPOX, TYR, NQO1 KMT2A 1709/4885MEN1 4432/4885KDM4C 496/4885
US-20200131193-A1 PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES PPOX, TYR, NQO1 KMT2A 1829/4885MEN1 4353/4885KDM4C 615/4885
US-10792361-B2 Lipids and lipid compositions for the delivery of active agents LIPA, LPAR1, LPAR4 KMT2A 3113/4885MEN1 1520/4885KDM4C 1908/4885
US-10729775-B2 Lipids and lipid compositions for the delivery of active agents LIPA, LPAR1, LPAR4 KMT2A 3113/4885MEN1 1520/4885KDM4C 1908/4885
US-20230212103-A1 POLYETHYLENE GLYCOL DERIVATIVE AND USE THEREOF RPN2, MPDU1, RPN1 KMT2A 4395/4885MEN1 2947/4885KDM4C 3875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.