Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24380155 | 0.80 | THRB (0.55) | PKMALDH1A1AKR1B1KIF11THRB | |
| SCHEMBL11774801 | 0.79 | KDM4E (0.43) | PKMKDM4EALDH1A1KIF11 | |
| SCHEMBL11773416 | 0.76 | KDM4E (0.44) | PKMKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| Benzoic Acid SCHEMBL11773028 | 0.74 | TSHR (0.45) | PKMKDM4EALDH1A1KIF11TDP1 | |
| SCHEMBL8256334 | 0.74 | KDM4E (0.51) | PKMKDM4EALDH1A1KIF11THRB | |
| SCHEMBL7326617 | 0.74 | KDM4E (0.56) | PKMKDM4EALDH1A1KIF11KMT2A | |
| Hydrochloric Acid SCHEMBL11776858 | 0.72 | KDM4E (0.50) | PKMKDM4EKIF11MAPT | |
| SCHEMBL1378915 | 0.72 | AKR1B1 (0.42) | PKMKDM4EALDH1A1AKR1B1KIF11 | |
| SCHEMBL11852375 | 0.70 | KDM4E (0.49) | PKMKDM4EALDH1A1KIF11THRB | |
| SCHEMBL28435630 | 0.69 | CYP3A4 (0.37) | KDM4EAKR1B1KIF11APEX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |