Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2675351 | 0.89 | KDM4E (1.00) | KDM4ELMNAMEN1KMT2ARECQL | |
| SCHEMBL2610312 | 0.83 | KDM4E (0.71) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL10445864 | 0.79 | LMNA (0.66) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL30309505 | 0.79 | LMNA (0.66) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL9143692 | 0.79 | LMNA (0.64) | KDM4ELMNAMEN1KMT2ARECQL | |
| SCHEMBL2676151 | 0.75 | KDM4E (0.73) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL23071158 | 0.74 | LMNA (0.58) | KDM4ELMNAMEN1KMT2ARECQL | |
| SCHEMBL362582 | 0.73 | LMNA (0.57) | KDM4ELMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL21383288 | 0.73 | MAPK1 (0.58) | KDM4ELMNAMEN1KMT2ARECQL | |
| SCHEMBL2676912 | 0.73 | KDM4E (0.65) | KDM4ELMNAMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |