⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828107 | 1.00 | — | — | |
| SCHEMBL7831548 | 0.91 | NFKB1 (0.31) | — | |
| SCHEMBL7828982 | 0.89 | MAPT (0.30) | — | |
| SCHEMBL7828985 | 0.89 | MAPT (0.30) | — | |
| SCHEMBL7828449 | 0.83 | — | — | |
| SCHEMBL7828445 | 0.83 | — | — | |
| SCHEMBL7828112 | 0.83 | — | — | |
| SCHEMBL7816245 | 0.82 | — | — | |
| SCHEMBL7816242 | 0.82 | — | — | |
| SCHEMBL7825032 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833825-B1 | 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES | BIOTA SCIENT MANAGEMENT (AU) | 2001-09-26 | — | — | EP | disclosed |
| US-5990156-A | 6-Carboxamido dihydropyran derivatives | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 1999-11-23 | — | — | US | disclosed |
| EP-0833825-A4 | 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES | BIOTA SCIENT MANAGEMENT (AU) | 1998-10-07 | — | — | EP | disclosed |
| EP-0833825-A1 | 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996036628-A1 | 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 1996-11-21 | — | — | WO | disclosed |