SCHEMBL7828982

SCHEMBL7828982

CC(=O)N[C@@H]1[C@@H](N/C(=N\C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)C=C(C(=O)OC(c2ccccc2)c2ccccc2)O[C@H]1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7828985 1.00 MAPT (0.30) MAPT
SCHEMBL7824697 0.89 NFKB1 (0.34) MAPT
SCHEMBL7828107 0.89
SCHEMBL7828109 0.89
SCHEMBL7828449 0.88
SCHEMBL7828445 0.88
SCHEMBL7816245 0.88
SCHEMBL7825032 0.88
SCHEMBL7816242 0.88
SCHEMBL7829023 0.86 NEU2 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0833825-B1 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES BIOTA SCIENT MANAGEMENT (AU) 2001-09-26 EP disclosed
US-5990156-A 6-Carboxamido dihydropyran derivatives BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) 1999-11-23 US disclosed
EP-0833825-A4 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES BIOTA SCIENT MANAGEMENT (AU) 1998-10-07 EP disclosed
EP-0833825-A1 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) 1998-04-08 EP disclosed
WO-1996036628-A1 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) 1996-11-21 WO disclosed