Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11709313 | 0.81 | LMNA (0.56) | HPGDLMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8563381 | 0.79 | HPGD (0.62) | HPGDLMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2313979 | 0.78 | SLC1A3 (0.81) | HPGDLMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1771059 | 0.78 | HPGD (0.60) | HPGDLMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8984826 | 0.78 | SLC1A3 (0.81) | HPGDLMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL15971325 | 0.78 | SLC1A3 (0.81) | HPGDLMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10404583 | 0.77 | HPGD (0.59) | HPGDLMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6062563 | 0.77 | LMNA (0.59) | HPGDLMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3021548 | 0.77 | LMNA (0.86) | HPGDLMNATSHRMAPTGAA | |
| SCHEMBL11601130 | 0.77 | LMNA (0.59) | HPGDLMNASLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |