Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747178 | 0.85 | KDM1A (0.54) | HPGDLMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13870224 | 0.84 | SMN1; SMN2 (0.63) | HPGDLMNAMAPTGAAALDH1A1 | |
| SCHEMBL7494278 | 0.82 | HPGD (0.55) | HPGDLMNATSHREPHX2MAPT | |
| SCHEMBL7494284 | 0.82 | HPGD (0.55) | HPGDLMNATSHREPHX2MAPT | |
| SCHEMBL5907668 | 0.81 | HPGD (0.67) | HPGDLMNATSHREPHX2MAPT | |
| SCHEMBL13778192 | 0.80 | RAB9A (0.51) | HPGDLMNAEPHX2MAPTGAA | |
| SCHEMBL8534248 | 0.79 | HPGD (0.56) | HPGDLMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8984826 | 0.79 | SLC1A3 (0.81) | HPGDLMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1771059 | 0.79 | HPGD (0.60) | HPGDLMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL15971325 | 0.79 | SLC1A3 (0.81) | HPGDLMNASLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490175-B1 | Process for the treatment of the cristallization mother liquors of the resolution of 1-(4-chlorophenyl)ethylamine | BAYER AG (DE) | 1994-09-28 | — | — | EP | claimed |
| US-5144077-A | PROCESS FOR WORKING UP THE CRYSTALLIZATION MOTHER LIQUOR FROM THE RESOLUTION OF THE RACEMATE OF 1-(4-CHLOROPHENYL)-ETHYLAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-01 | — | — | US | claimed |
| JP-5025100-A | — | — | None | — | — | JP | disclosed |
| US-5773656-A | Process for the preparation of optically active 1-aryl-alkylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| JP-H0525100-A | RECOVERY OF RESOLVED RACEMIC 1-(4-CHLOROPHENYL)-ETHYLAMINE CRYSTALS FROM MOTHER LIQUOR | BAYER AG | 1993-02-02 | — | — | JP | disclosed |
| US-5144077-A | PROCESS FOR WORKING UP THE CRYSTALLIZATION MOTHER LIQUOR FROM THE RESOLUTION OF THE RACEMATE OF 1-(4-CHLOROPHENYL)-ETHYLAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-01 | — | — | US | disclosed |
| US-5144077-A | PROCESS FOR WORKING UP THE CRYSTALLIZATION MOTHER LIQUOR FROM THE RESOLUTION OF THE RACEMATE OF 1-(4-CHLOROPHENYL)-ETHYLAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-01 | — | — | US | disclosed |