Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MASP2 | O00187 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655894 | 0.88 | POLB (0.56) | HSD17B10POLBNAPRTCYP2C19ALDH1A1 | |
| SCHEMBL31046806 | 0.88 | PTPN11 (0.55) | HSD17B10POLBNAPRTCYP2C19ALDH1A1 | |
| SCHEMBL25258585 | 0.88 | PTPN11 (0.55) | HSD17B10POLBNAPRTCYP2C19ALDH1A1 | |
| SCHEMBL950942 | 0.88 | POLB (0.62) | HSD17B10POLBNAPRTCYP2C19ALDH1A1 | |
| SCHEMBL11796151 | 0.87 | MMP2 (0.52) | HSD17B10POLBNAPRTCYP2C19ALDH1A1 | |
| SCHEMBL2113108 | 0.87 | ALDH1A1 (0.57) | HSD17B10POLBCYP2C19ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9056132 | 0.85 | MMP2 (0.50) | HSD17B10POLBNAPRTCYP2C19ALDH1A1 | |
| SCHEMBL10397861 | 0.84 | ALDH1A1 (0.48) | HSD17B10POLBNAPRTCYP2C19ALDH1A1 | |
| SCHEMBL17799564 | 0.82 | KDM4E (0.62) | HSD17B10POLBNAPRTCYP2C19ALDH1A1 | |
| SCHEMBL29071479 | 0.82 | BDKRB1 (0.48) | NAPRTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |