SCHEMBL7828510

SCHEMBL7828510

CCOC(=O)C(CC)(CC)P(=O)(O)OOCCOC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
MMP8 P22894 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL543816 0.87 CYP4F2 (0.35) CYP4F2CYP4A11MMP8L3MBTL1
SCHEMBL9274852 0.80 TDP1 (0.44) L3MBTL1
SCHEMBL10930331 0.80 CYP4F2 (0.37) CYP4F2CYP4A11MMP8L3MBTL1
SCHEMBL7826828 0.78 MMP8 (0.43) MMP8L3MBTL1
SCHEMBL9275213 0.78 MMP8 (0.41) MMP8L3MBTL1
SCHEMBL8045727 0.78 MMP8 (0.35) CYP4F2CYP4A11MMP8
SCHEMBL5451691 0.76 MAPT (0.37) CYP4F2CYP4A11MMP8
SCHEMBL4335915 0.76 MMP8 (0.37) CYP4F2CYP4A11MMP8
SCHEMBL3133963 0.75 CYP4F2 (0.36) CYP4F2CYP4A11MMP8L3MBTL1
SCHEMBL1072447 0.75 CYP4F2 (0.36) CYP4F2CYP4A11MMP8L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648212-B1 BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES AS PHARMACEUTICAL SMITHKLINE BEECHAM PLC (GB) 2001-10-24 EP disclosed
EP-1000938-A1 Heterocyclic compounds as pharmaceuticals SMITHKLINE BEECHAM PLC (GB) 2000-05-17 EP disclosed
US-6048883-A HYPOGLYCEMIC AGENT SMITHKLINE BEECHAM P.L.C. (GB) 2000-04-11 US disclosed
US-5869495-A TREATMENT AND/OR PROPHYLAXIS OF HYPERGLYCAEMIA SMITHKLINE BEECHAM P.L.C. (GB) 1999-02-09 US disclosed
US-5827865-A TREATMENT AND-OR PROPHYLAXIS OF HYPERGLYEMIA SMITHKLINE BEECHAM P.L.C. (GB) 1998-10-27 US disclosed
EP-0648212-A1 HETEROCYCLIC COMPOUNDS AS PHARMACEUTICAL SMITHKLINE BEECHAM PLC (GB) 1995-04-19 EP disclosed
WO-1994001420-A1 HETEROCYCLIC COMPOUNDS AS PHARMACEUTICAL SMITHKLINE BEECHAM PLC (GB) 1994-01-20 WO disclosed