Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11054574 | 0.98 | ALDH1A1 (0.43) | ALDH1A1TP53HPGDHTTHSD17B10 | |
| SCHEMBL9616010 | 0.86 | HPGD (0.42) | ALDH1A1TP53HPGDHTTHSD17B10 | |
| SCHEMBL9159642 | 0.86 | ITGB2 (0.45) | ALDH1A1TP53HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL9162991 | 0.83 | HPGD (0.40) | ALDH1A1TP53HPGDHTTHSD17B10 | |
| SCHEMBL11601549 | 0.79 | KMO (0.35) | HSD17B10CYP2C9CYP2C19TSHRKMO | |
| SCHEMBL10779011 | 0.79 | TSHR (0.50) | TP53HTTHSD17B10CYP2C9CYP2C19 | |
| SCHEMBL11091141 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HPGDHSD17B10CYP2C9CYP2C19 | |
| SCHEMBL11519814 | 0.77 | POLB (0.51) | ALDH1A1TP53HPGDHTTHSD17B10 | |
| SCHEMBL10784200 | 0.73 | HSD17B10 (0.68) | ALDH1A1HPGDHTTHSD17B10CYP2C9 | |
| SCHEMBL8779725 | 0.72 | TP53 (0.44) | ALDH1A1TP53HPGDHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496396-B1 | 2,5-dichlorophenylthioglycolic acid derivative and method for its production | SUMITOMO SEIKA CHEMICALS (JP) | 1995-04-05 | — | — | EP | claimed |
| US-5352821-A | Reacting 2,4,5-trichlorobenzenesulfonate with thioglycolic acid in presence of base, reacting with mineral acid or aqueous solution thereof | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1994-10-04 | — | — | US | claimed |
| EP-0496396-A2 | 2,5-dichlorophenylthioglycolic acid derivative and method for its production | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1992-07-29 | — | — | EP | claimed |
| EP-0290886-B1 | PROCESS FOR THE PREPARATION OF 2,5-DICHLOROPHENYLTHIOGLYCOLIC ACID | CASSELLA Aktiengesellschaft (DE) | 1992-01-08 | — | — | EP | claimed |
| US-4555580-A | FROM PHENYLTHIOGLYCOLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-26 | — | — | US | claimed |
| JP-5086019-A | — | — | None | — | — | JP | disclosed |
| JP-5178816-A | — | — | None | — | — | JP | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| EP-0496396-B1 | 2,5-dichlorophenylthioglycolic acid derivative and method for its production | SUMITOMO SEIKA CHEMICALS (JP) | 1995-04-05 | — | — | EP | disclosed |
| EP-0496396-B1 | 2,5-dichlorophenylthioglycolic acid derivative and method for its production | SUMITOMO SEIKA CHEMICALS (JP) | 1995-04-05 | — | — | EP | disclosed |
| EP-0488237-B1 | Method for producing dichlorophenylthioglycolic acid | SUMITOMO SEIKA CHEMICALS (JP) | 1995-03-01 | — | — | EP | disclosed |
| US-4689087-A | Process for the preparation of an organic pigment on the basis of 4,4',7,7'-tetrachloro-thio-indigo | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-08-25 | — | — | US | disclosed |
| US-4652660-A | OXIDATION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| US-4617403-A | Process for preparing a pigment based on 4,4',7,7'-tetrachlorothioindigo | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-10-14 | — | — | US | disclosed |
| US-4555580-A | FROM PHENYLTHIOGLYCOLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-26 | — | — | US | disclosed |
| US-4461911-A | FROM THIOGLYCOLIC ACID AND AN ARYLDIAZONIUM SALT, COPPER SALT, ACID MEDIUM | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-24 | — | — | US | disclosed |
| US-4431824-A | Preparation of 4,4',7,7'-tetrachlorothioindigo pigments of high color strength | BASF AKTIENGESELLSCHAFT (DE) | 1984-02-14 | — | — | US | disclosed |
| US-4332955-A | Preparation of transparent pigmentary forms of 4,4',7,7'-tetrachlorothioindigo | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-01 | — | — | US | disclosed |
| US-4260778-A | Process for the preparation of thioindigo compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |