SCHEMBL7828608

SCHEMBL7828608

O=C(O)c1ccccc1C(=O)c1ccc2ccccc2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 3/20 0.70
CDC25A P30304 1/20 0.70
HSD17B10 Q99714 1/20 0.70
AKR1C3 P42330 3/20 0.62
ALDH1A1 P00352 3/20 0.62
ATM Q13315 1/20 0.59
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
MAPT P10636 1/20 0.58
MAPK1 P28482 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
NR4A1 P22736 1/20 0.58
POLB P06746 2/20 0.57
CES2 O00748 1/20 0.57
CES1 P23141 1/20 0.57
KDM4E B2RXH2 1/20 0.53
LMNA P02545 1/20 0.53
ALOX15 P16050 1/20 0.52
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27960603 0.86 CDC25B (0.72) CDC25BCDC25AHSD17B10AKR1C3ALDH1A1
SCHEMBL9624756 0.84 CDC25B (0.64) CDC25BCDC25AHSD17B10AKR1C3ALDH1A1
Phthalic Acid SCHEMBL28035344 0.84 PTPN1 (0.63) CDC25BCDC25AHSD17B10AKR1C3ALDH1A1
SCHEMBL7560635 0.84 KDM4E (0.66) CDC25BCDC25AHSD17B10AKR1C3ALDH1A1
SCHEMBL1527575 0.84 CDC25B (0.58) CDC25BCDC25AHSD17B10AKR1C3ALDH1A1
SCHEMBL30100406 0.84 CDC25B (0.58) CDC25BCDC25AHSD17B10AKR1C3ALDH1A1
SCHEMBL17060507 0.84 CES2 (0.55) CDC25BCDC25AHSD17B10ALDH1A1MEN1
SCHEMBL7558052 0.82 CDC25B (0.57) CDC25BCDC25AHSD17B10AKR1C3ALDH1A1
SCHEMBL2058645 0.82 CDC25B (1.00) CDC25BCDC25AHSD17B10AKR1C3ALDH1A1
SCHEMBL3074652 0.82 CDC25B (1.00) CDC25BCDC25AHSD17B10AKR1C3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-54055559-A None JP disclosed
CN-119613306-A Thiocarbonyl-containing ethyl thiobenzoate compound and preparation method thereof 淮北师范大学 2025-03-14 CN disclosed
CN-1139589-C Tetrahydroimidazo [2,1-a] isoquinoline derivatives ��˹��ŵ�� 2004-02-25 CN disclosed
EP-0887349-B1 Tetrahydroimidazo (2,1-a)isoquinoline derivatives AKZO NOBEL NV (NL) 2001-11-28 EP disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
US-5994366-A PSYCHOLOGICAL DISORDERS AKZO NOBEL NV (NL) 1999-11-30 US disclosed
CN-1203916-A Tetrahydroimidazo [2,1-a] isoquinoline derivatives AKZO NOBEL NV (NL) 1999-01-06 CN disclosed
EP-0887349-A1 Tetrahydroimidazo (2,1-a)isoquinoline derivatives Akzo Nobel N.V. (NL) 1998-12-30 EP disclosed
EP-0569457-B1 USE OF THIAZOLO-[2,3-A]ISOINDOLE DERIVATIVES AS ANTIVIRAL MEDICAMENTS AND NOVEL THIAZOLO- [2,3-A]ISOINDOLE DERIVATIVES BOEHRINGER MANNHEIM GMBH (DE) 1995-06-14 EP disclosed
EP-0407808-B1 Catalyst, process for preparation of same, and process for polymerization of olefins using same SHOWA DENKO KK (JP) 1994-12-07 EP disclosed
EP-0569457-A1 USE OF THIAZOLO- 2,3-A]ISOINDOLE DERIVATIVES AS ANTIVIRAL MEDICAMENTS AND NOVEL THIAZOLO- 2,3-A]ISOINDOLE DERIVATIVES. BOEHRINGER MANNHEIM GMBH (DE) 1993-11-18 EP disclosed
US-5208302-A Coordination Catalysts Containing a Ketoester, Stereoregular SHOWA DENKO K.K. (JP) 1993-05-04 US disclosed
EP-0325825-B1 PHOSPHORESCENT MATERIALS THE POST OFFICE (GB) 1992-09-16 EP disclosed
WO-1992013863-A1 USE OF THIAZOLO-[2,3-A]ISOINDOLE DERIVATIVES AS ANTIVIRAL MEDICAMENTS AND NOVEL THIAZOLO-[2,3-A]ISOINDOLE DERIVATIVES BOEHRINGER MANNHEIM GMBH (DE) 1992-08-20 WO disclosed
US-5100580-A Polycyclic aromatic ketones, printing ink and paper coating, activator in amino resin matrix THE POST OFFICE (GB) 1992-03-31 US disclosed
EP-0407808-A2 Catalyst, process for preparation of same, and process for polymerization of olefins using same SHOWA DENKO KABUSHIKI KAISHA (JP) 1991-01-16 EP disclosed
EP-0325825-A1 Phosphorescent materials THE POST OFFICE (GB) 1989-08-02 EP disclosed
JP-S5455559-A 1,2-BENZANTHROQUINONEDISULFONIC ACID AND ITS SALT, THEIR PREPARATION, AND OXIDATION AND REDUCTION REAGENT THEREOF FOR WET TYPE DESULFURIZATION PROCESS MITSUI TOATSU CHEM INC 1979-05-02 JP disclosed
US-4058529-A Polycyclic amino derivatives of pyrrolidone and piperidone CIBA-GEIGY CORPORATION (US) 1977-11-15 US disclosed