Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.57 |
| ▸ | CDC25A | P30304 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701316 | 0.84 | HPGD (0.70) | CDC25BCDC25AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL9210385 | 0.83 | POLB (0.64) | CDC25BCDC25AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL7828608 | 0.82 | CDC25B (0.70) | CDC25BCDC25AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL7558044 | 0.81 | HPGD (0.58) | ALDH1A1KDM4EPOLBRAB9ANPC1 | |
| SCHEMBL2701032 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EPOLBRAB9ANPC1 | |
| SCHEMBL29717125 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EPOLBRAB9ANPC1 | |
| SCHEMBL10658386 | 0.79 | ALDH1A1 (0.54) | CDC25BCDC25AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL9218197 | 0.78 | HPGD (0.61) | CDC25BCDC25AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL9314585 | 0.78 | KDM4E (0.62) | CDC25BCDC25AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL7560635 | 0.78 | KDM4E (0.66) | CDC25BCDC25AHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052354-A1 | Paramagnetic DOTA derivatives, pharmaceutical agents that contain the latter, process for their production, and their use for MR imaging of necrosis and infarction | SCHERING AG | 2002-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052354-A1 | Paramagnetic DOTA derivatives, pharmaceutical agents that contain the latter, process for their production, and their use for MR imaging of necrosis and infarction | TNNI3, NPR1, LPXN | CDC25B 4031/4885CDC25A 4078/4885HSD17B10 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.