Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109424 | 0.88 | ALDH1A1 (0.59) | ALDH1A1POLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL7813937 | 0.86 | MAPT (0.69) | ALDH1A1POLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL7107371 | 0.82 | POLB (0.82) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL10365414 | 0.82 | MAPT (0.59) | ALDH1A1POLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL7566026 | 0.78 | ALDH1A1 (0.66) | ALDH1A1POLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL7282277 | 0.78 | ALDH1A1 (0.59) | ALDH1A1POLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL24040103 | 0.78 | POLB (0.70) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL7825018 | 0.78 | POLB (0.70) | ALDH1A1POLBRAB9AMAPTMEN1 | |
| SCHEMBL7828620 | 0.78 | ALDH1A1 (0.70) | ALDH1A1POLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL29908945 | 0.78 | HDAC8 (0.51) | ALDH1A1POLBRAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |