Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107371 | 0.91 | POLB (0.82) | ALDH1A1POLBGAAL3MBTL1MEN1 | |
| SCHEMBL7824236 | 0.86 | HDAC3 (0.71) | ALDH1A1POLBGAAL3MBTL1MEN1 | |
| SCHEMBL24040103 | 0.86 | POLB (0.70) | ALDH1A1POLBGAAL3MBTL1MEN1 | |
| SCHEMBL7825018 | 0.86 | POLB (0.70) | ALDH1A1POLBGAAL3MBTL1MEN1 | |
| SCHEMBL3152473 | 0.84 | CYP1A1 (0.79) | ALDH1A1POLBGAAL3MBTL1MEN1 | |
| SCHEMBL3806017 | 0.83 | MEN1 (0.73) | ALDH1A1POLBGAAL3MBTL1MEN1 | |
| SCHEMBL7566026 | 0.83 | ALDH1A1 (0.66) | ALDH1A1POLBGAAL3MBTL1MEN1 | |
| SCHEMBL13989319 | 0.82 | GAA (0.73) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL7824643 | 0.82 | GAA (0.77) | ALDH1A1POLBGAAL3MBTL1MEN1 | |
| SCHEMBL4084296 | 0.82 | POLB (0.66) | ALDH1A1POLBGAAL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |