Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824567 | 0.91 | HTT (0.75) | GAAL3MBTL1POLBHTTSMN1; SMN2 | |
| SCHEMBL8986265 | 0.88 | POLB (0.73) | GAAL3MBTL1POLBHTTSMN1; SMN2 | |
| SCHEMBL11642285 | 0.85 | POLB (0.69) | GAAL3MBTL1POLBHTTSMN1; SMN2 | |
| SCHEMBL10652806 | 0.85 | POLB (0.69) | GAAL3MBTL1POLBHTTSMN1; SMN2 | |
| SCHEMBL8443095 | 0.85 | POLB (0.69) | GAAL3MBTL1POLBHTTSMN1; SMN2 | |
| SCHEMBL17268200 | 0.84 | L3MBTL1 (0.81) | GAAL3MBTL1POLBHTTSMN1; SMN2 | |
| SCHEMBL9842944 | 0.84 | POLB (0.77) | GAAPOLBHTTSMN1; SMN2NPC1 | |
| SCHEMBL7107371 | 0.83 | POLB (0.82) | GAAL3MBTL1POLBHPGDALDH1A1 | |
| SCHEMBL7828620 | 0.82 | ALDH1A1 (0.70) | GAAL3MBTL1POLBSMN1; SMN2HPGD | |
| SCHEMBL9312707 | 0.82 | POLB (1.00) | POLBHTTSMN1; SMN2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |