Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA3 | P32297 | 3/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827263 | 1.00 | CHRNA3 (0.56) | CHRNA3CHRNB4CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7454572 | 0.99 | CHRNA3 (0.55) | CHRNA3CHRNB4CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7579647 | 0.92 | CHRNB2 (0.56) | CHRNA3CHRNB4CHRNB2CHRNA4 | |
| SCHEMBL7832089 | 0.91 | CHRNB2 (0.53) | CHRNA3CHRNB4CHRNB2CHRNA4 | |
| SCHEMBL7827645 | 0.91 | CHRNB2 (0.53) | CHRNA3CHRNB4CHRNB2CHRNA4 | |
| SCHEMBL7825983 | 0.90 | CHRNA3 (0.59) | CHRNA3CHRNB4CHRNB2CHRNA4 | |
| SCHEMBL7827554 | 0.90 | CHRNA3 (0.59) | CHRNA3CHRNB4CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7406502 | 0.89 | CHRNA3 (0.57) | CHRNA3CHRNB4CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7817371 | 0.89 | CHRNA3 (0.57) | CHRNA3CHRNB4CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7454719 | 0.84 | CHRNA3 (0.57) | CHRNA3CHRNB4CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846114-B1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LAB (US) | 2001-12-05 | — | — | EP | claimed |
| EP-0846114-B1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LAB (US) | 2001-12-05 | — | — | EP | disclosed |