Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.61 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614852 | 0.99 | CYP4F2 (0.63) | CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9614835 | 0.89 | CYP4F2 (0.60) | CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL27674003 | 0.82 | CYP4F2 (0.65) | CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL7831168 | 0.82 | CYP1A1 (0.54) | CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9883405 | 0.80 | MEN1 (0.60) | CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9883387 | 0.80 | MEN1 (0.60) | CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9748816 | 0.80 | TDP1 (0.49) | TDP1L3MBTL1 | |
| SCHEMBL9749184 | 0.79 | CYP1A2 (0.57) | SMN1; SMN2CYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL9749632 | 0.79 | MTNR1A (0.50) | — | |
| SCHEMBL30594122 | 0.79 | CYP4F2 (0.68) | CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737671-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5804601-A | USEFUL FOR TREATING ALZHEIMER'S DISEASE, MULTIPLE SCLEROSIS, BACTERIAL OR VIRAL MENINGITIS, DOWN'S SYNDROME AND PARKINSON'S DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-08 | — | — | US | disclosed |
| EP-0737671-A2 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-10-16 | — | — | EP | disclosed |