Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614851 | 0.84 | LDHA (0.46) | — | |
| SCHEMBL9614852 | 0.81 | CYP4F2 (0.63) | TDP1L3MBTL1 | |
| SCHEMBL9749099 | 0.80 | TDP1 (0.48) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL7829068 | 0.80 | CYP4F2 (0.61) | TDP1L3MBTL1 | |
| SCHEMBL9614835 | 0.79 | CYP4F2 (0.60) | — | |
| SCHEMBL9749227 | 0.78 | CA2 (0.41) | MAPK1 | |
| SCHEMBL10915187 | 0.78 | — | — | |
| SCHEMBL1203591 | 0.76 | — | — | |
| SCHEMBL2005766 | 0.74 | TYR (0.51) | — | |
| SCHEMBL11203242 | 0.74 | TDP1 (0.55) | TDP1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201071-B1 | 2-SUBSTITUTED-1-NAPHTHOLS AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-03-04 | — | — | EP | claimed |