Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.32 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829244 | 1.00 | KMT2A (0.36) | KMT2AMEN1POLBNPSR1MAPT | |
| SCHEMBL7830131 | 0.83 | LMNA (0.35) | KMT2AMEN1LMNAALDH1A1KDM4E | |
| SCHEMBL8005624 | 0.82 | SRD5A2 (0.36) | KMT2AMEN1POLBNPSR1MAPT | |
| SCHEMBL8005622 | 0.82 | SRD5A2 (0.36) | KMT2AMEN1POLBNPSR1MAPT | |
| SCHEMBL8000238 | 0.78 | LMNA (0.34) | KMT2AMEN1POLBNPSR1LMNA | |
| SCHEMBL8000241 | 0.78 | LMNA (0.34) | KMT2AMEN1POLBNPSR1LMNA | |
| SCHEMBL8002328 | 0.74 | KDM4E (0.33) | KMT2AMEN1LMNAALDH1A1KDM4E | |
| SCHEMBL8002325 | 0.74 | KDM4E (0.33) | KMT2AMEN1LMNAALDH1A1KDM4E | |
| SCHEMBL7837271 | 0.74 | UTS2R (0.33) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL7837274 | 0.74 | UTS2R (0.33) | KMT2AMEN1POLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737672-B1 | Method of producing triazine derivatives | TAKEDA SCHERING PLOUGH ANIMAL (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0737672-A2 | Method of producing triazine derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-16 | — | — | EP | disclosed |