Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002325 | 1.00 | KDM4E (0.33) | KDM4EALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL8000238 | 0.96 | LMNA (0.34) | KDM4EALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL8000241 | 0.96 | LMNA (0.34) | KDM4EALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL8001906 | 0.92 | LMNA (0.32) | KDM4EALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL8001911 | 0.92 | LMNA (0.32) | KDM4EALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL7998519 | 0.85 | L3MBTL1 (0.32) | KDM4EALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL7998524 | 0.85 | L3MBTL1 (0.32) | KDM4EALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL7830131 | 0.83 | LMNA (0.35) | KDM4EALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL8005622 | 0.83 | SRD5A2 (0.36) | KDM4EALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL8005624 | 0.83 | SRD5A2 (0.36) | KDM4EALDH1A1LMNAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294536-B1 | CONTROL OF PROTOZOA AND REDUCTION IN THE INCIDENCE OF ASSOCIATED DISEASES AND DEATH AND CONSEQUENT IMPROVEMENT IN RETARDED GROWTH AND GENERAL CONDITION AND PREVENTING DECREASE GROWTH AND GENERAL CONDITION | TAKEDA SCHERING-PLOUGH ANIMAL HEALTH K.K. (JP) | 2001-09-25 | — | — | US | disclosed |
| WO-1999011634-A1 | TRIAZINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-11 | — | — | WO | disclosed |