Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156093 | 0.90 | ALOX5AP (0.44) | ALOX5APFEN1GPR119F2RL3CHEK2 | |
| SCHEMBL6585343 | 0.89 | ALOX5AP (0.43) | ALOX5APFEN1GPR119F2RL3CHEK2 | |
| SCHEMBL7675594 | 0.89 | ALOX5AP (0.43) | ALOX5APFEN1GPR119F2RL3CHEK2 | |
| Hydrochloric Acid SCHEMBL6587211 | 0.89 | ALOX5AP (0.43) | ALOX5APFEN1GPR119F2RL3CHEK2 | |
| SCHEMBL6583182 | 0.85 | ALOX5AP (0.41) | ALOX5APFEN1GPR119F2RL3CHRNA3 | |
| SCHEMBL6585264 | 0.85 | ALOX5AP (0.42) | ALOX5APFEN1GPR119F2RL3CHRNB2 | |
| SCHEMBL7477731 | 0.85 | ALOX5AP (0.42) | ALOX5APFEN1GPR119F2RL3CHRNB2 | |
| SCHEMBL6585553 | 0.85 | GPR119 (0.41) | ALOX5APFEN1GPR119F2RL3 | |
| SCHEMBL6583129 | 0.84 | GPR119 (0.38) | ALOX5APFEN1GPR119F2RL3CHRNB2 | |
| SCHEMBL6588750 | 0.83 | ALOX5AP (0.38) | ALOX5APFEN1GPR119CHRNA3CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846114-B1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LAB (US) | 2001-12-05 | — | — | EP | disclosed |