Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829961 | 1.00 | LMNA (0.60) | LMNAHPGDPOLBATMHTT | |
| SCHEMBL7829044 | 0.86 | LMNA (0.59) | LMNAHPGDPOLBATMHTT | |
| SCHEMBL7833276 | 0.84 | LMNA (0.57) | LMNAHPGDPOLBATMHTT | |
| SCHEMBL7820871 | 0.82 | LMNA (0.49) | LMNAHPGDPOLBATMHTT | |
| SCHEMBL7829459 | 0.81 | LMNA (0.67) | LMNAHPGDPOLBATMHTT | |
| SCHEMBL7829947 | 0.81 | LMNA (0.67) | LMNAHPGDPOLBATMHTT | |
| SCHEMBL12046948 | 0.80 | LMNA (0.68) | LMNAHPGDPOLBATMHTT | |
| SCHEMBL7835431 | 0.79 | SMN1; SMN2 (0.89) | LMNAHPGDPOLBATMHTT | |
| SCHEMBL4700801 | 0.79 | HTT (0.69) | LMNAHPGDPOLBATMHTT | |
| SCHEMBL7835167 | 0.79 | SMN1; SMN2 (0.89) | LMNAHPGDPOLBATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737671-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| EP-0737671-A2 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-10-16 | — | — | EP | disclosed |