Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672708 | 0.85 | — | — | |
| SCHEMBL1186649 | 0.71 | KCNH2 (0.50) | NOS2 | |
| SCHEMBL1187648 | 0.71 | KCNH2 (0.50) | NOS2 | |
| SCHEMBL1188056 | 0.71 | KCNH2 (0.50) | NOS2 | |
| SCHEMBL4928617 | 0.69 | — | — | |
| SCHEMBL3582066 | 0.67 | NOS3 (0.33) | NOS3NOS2 | |
| SCHEMBL1767952 | 0.67 | HRH4 (0.41) | NOS3NOS2 | |
| SCHEMBL12228994 | 0.65 | NOS3 (0.44) | NOS3NOS2 | |
| SCHEMBL10051193 | 0.65 | NOS3 (0.50) | NOS3NOS2 | |
| SCHEMBL7285872 | 0.64 | NOS2 (0.46) | NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820997-B1 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2001-07-25 | — | — | EP | disclosed |
| CN-1066450-C | Pyrazolo [1, 5 -alpha] pyrimidine derivatives | OTSUKA PHARMA CO LTD (JP) | 2001-05-30 | — | — | CN | disclosed |
| US-5985882-A | ANALGESICS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| CN-1181082-A | Pyrazolo [1, 5-alpha ] pyrimidine derivatives | OTSUKA PHARMACEUTICAL FACOTORY (JP) | 1998-05-06 | — | — | CN | disclosed |
| EP-0820997-A1 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-01-28 | — | — | EP | disclosed |