SCHEMBL7829482

SCHEMBL7829482

CCCCCCCCc1ccccc1S(=O)(=O)NC(C)C=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.40
RECQL P46063 1/20 0.40
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
CYSLTR2 Q9NS75 6/20 0.37
CYSLTR1 Q9Y271 6/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2C19 P33261 2/20 0.37
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PTPN1 P18031 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP2C9 P11712 1/20 0.36
CA12 O43570 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9594245 0.82 LIPG (0.40) LIPGRECQLNR1H2NR1H3CYSLTR2
SCHEMBL11406272 0.77 LIPG (0.46) LIPGRECQLNR1H2NR1H3THRA
SCHEMBL226295 0.77 RECQL (0.52) LIPGRECQLNR1H2NR1H3THRA
SCHEMBL4596089 0.76 MMP9 (0.50) CYSLTR2CYSLTR1CA12CA9
SCHEMBL4595506 0.76 MMP9 (0.50) CYSLTR2CYSLTR1CA12CA9
SCHEMBL31367739 0.76 CA12 (0.51) LIPGRECQLNR1H2NR1H3CYP1A2
SCHEMBL11469686 0.75 LIPG (0.50) LIPGRECQLNR1H2NR1H3THRA
SCHEMBL1403964 0.75 LIPG (0.50) LIPGRECQLNR1H2NR1H3THRA
SCHEMBL11361072 0.75 LIPG (0.50) LIPGRECQLNR1H2NR1H3THRA
SCHEMBL1404117 0.75 LIPG (0.50) LIPGRECQLNR1H2NR1H3THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5235058-A Photographic couplers FUJI PHOTO FILM CO., LTD. (JP) 1993-08-10 US claimed
EP-0476659-B1 A 3(5)-Hydrazinopyrazole compound FUJI PHOTO FILM CO LTD (JP) 2001-12-19 EP disclosed
US-5235058-A Photographic couplers FUJI PHOTO FILM CO., LTD. (JP) 1993-08-10 US disclosed
EP-0476659-A1 A 3(5)-Hydrazinopyrazole compound Fuji Photo Film Co., Ltd. (JP) 1992-03-25 EP disclosed