Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20559746 | 0.86 | PARP1 (0.61) | ALDH1A1HTTSMN1; SMN2MAPTMEN1 | |
| SCHEMBL20559230 | 0.86 | PARP1 (0.61) | ALDH1A1HTTSMN1; SMN2MAPTMEN1 | |
| SCHEMBL10797613 | 0.86 | GRM4 (0.64) | ALDH1A1TDP1POLBHTTSMN1; SMN2 | |
| SCHEMBL10797609 | 0.86 | GRM4 (0.64) | ALDH1A1TDP1POLBHTTSMN1; SMN2 | |
| SCHEMBL10905957 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TDP1POLBHTTSMN1; SMN2 | |
| SCHEMBL10905846 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TDP1POLBHTTSMN1; SMN2 | |
| SCHEMBL730838 | 0.82 | ALDH1A1 (0.67) | ALDH1A1POLBHTTSMN1; SMN2MAPT | |
| SCHEMBL12190079 | 0.80 | RXFP1 (0.53) | ALDH1A1TDP1POLBHTTSMN1; SMN2 | |
| SCHEMBL7822572 | 0.78 | ALDH1A1 (0.71) | ALDH1A1TDP1POLBHTTSMN1; SMN2 | |
| SCHEMBL19638388 | 0.75 | RXFP1 (0.73) | ALDH1A1POLBSMN1; SMN2MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |