Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1069498 | 0.78 | ACP3 (0.47) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL7829850 | 0.77 | NPSR1 (0.46) | NPSR1FFAR4SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8353773 | 0.77 | ACP3 (0.51) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| Benzene SCHEMBL10698838 | 0.71 | GPR84 (0.89) | FFAR4GPR84FFAR1KMT2AMEN1 | |
| SCHEMBL18126611 | 0.70 | MAPT (0.66) | SMN1; SMN2KMT2AALDH1A1MAPK1MAPT | |
| Isophthalic Acid SCHEMBL2380785 | 0.69 | GPR84 (0.57) | FFAR4GPR84FFAR1SMN1; SMN2LMNA | |
| Azelaic Acid SCHEMBL11389879 | 0.69 | GPR84 (0.57) | FFAR4GPR84FFAR1SMN1; SMN2LMNA | |
| Isophthalic Acid SCHEMBL29100400 | 0.69 | GPR84 (0.57) | FFAR4GPR84FFAR1SMN1; SMN2LMNA | |
| SCHEMBL810858 | 0.69 | NPC1 (0.53) | — | |
| Hexanoate SCHEMBL29016049 | 0.69 | AKR1B1 (0.57) | FFAR4GPR84FFAR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |